Last reviewed November 6, 2026.
The short answer
Retatrutide is an investigational medicine. It is not FDA-approved. Our practice does not offer it, and no one can lawfully compound it for patients. If you are interested in it, the best step today is a visit to talk about the FDA-approved options that exist now.
What retatrutide is
Retatrutide is an experimental weight-management medicine being developed by Eli Lilly and Company. It is being studied as a once-weekly injection. It is designed to act on three hormone receptors (GIP, GLP-1 and glucagon), which is why it is sometimes called a "triple agonist." For comparison, tirzepatide acts on two of these, and semaglutide acts on one.
You may have seen headlines about retatrutide. Those come from clinical trials, which are still being studied and reviewed. We do not repeat trial results here. A trial result is not an FDA approval, and the FDA has not yet reviewed it.
Where it stands
As of this writing, retatrutide is in late-stage clinical trials. A regulatory filing with the FDA is expected in 2027. Expected dates in drug development often change. Even after a filing, the FDA takes time to review a new medicine before deciding whether to approve it.
We will update this page when there is real news. If retatrutide is approved, Dr. Conkright will decide whether and for whom to prescribe it, the same way he decides for every medicine.
How a new medicine reaches patients
A new medicine goes through several stages before a doctor can prescribe it. It is tested in clinical trials, usually over several years. The company then files an application with the FDA. The FDA reviews the data on how well it works, its side effects and how it is made, and decides whether to approve it. If it is approved, it gets a label that sets out its approved use, warnings and directions.
Only then can it be prescribed for that use. Retatrutide has not reached that point.
Why you cannot lawfully get it today
Because retatrutide is not FDA-approved, a doctor cannot prescribe it. It also cannot lawfully be compounded by a pharmacy for patients. Compounding pharmacies may only use certain ingredients, and an investigational drug that is not part of an approved medicine is not one of them.
Today it is given only in research studies, which are listed at ClinicalTrials.gov.
A word of caution about online offers
Some websites sell products they call retatrutide, often labeled "for research use only" or "not for human use." Those products are not FDA-approved, are not lawfully compounded, and are not made for people. You have no way of knowing what is actually in them. We strongly advise against buying them.
If you have already used one, tell Dr. Conkright at your visit. Bring the label if you have it. He will not judge you. He will help you think through your options.
What you can do now
You do not have to wait. There are FDA-approved weight-management medicines available today, as pills and as injections:
- Wegovy (semaglutide injection) and the Wegovy pill: see our semaglutide page
- Zepbound (tirzepatide injection): see our tirzepatide page
- Foundayo (orforglipron) and the Wegovy pill: see our weight loss pills page
These are approved by the FDA for chronic weight management. Whether one fits you is Dr. Conkright's decision at your in-person visit, after a health screen. He sees every patient himself.
Our fees are on the cost page, and the visit is explained on how to start.
Questions
Is retatrutide FDA-approved?
No. It is an investigational medicine still in clinical trials.
Do you offer retatrutide?
No. We do not offer it, and no one can lawfully compound it for patients.
When will retatrutide be available?
No one can say for sure. A regulatory filing is expected in 2027, and FDA review takes time after that.
Can a compounding pharmacy make retatrutide?
Not lawfully. It is not FDA-approved and is not an ingredient pharmacies are permitted to compound with.
What about "research" retatrutide sold online?
Those products are not approved for people, are not lawfully compounded, and their contents are unknown. We advise against them.
What can I take instead?
FDA-approved options exist now, as pills and injections. Dr. Conkright decides at your visit whether one fits you.